ATP7B, ATPase copper transporting beta, 540

N. diseases: 182; N. variants: 333
Disease: Liver neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.340 Biomarker group BEFREE Copper-resistant hepatoma HepG2 cell lines lacking ATP7B were generated. 28805879 2017
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.340 Biomarker group BEFREE The effect of zinc and D-penicillamine in a stable human hepatoma ATP7B knockout cell line. 24892424 2014
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.340 Biomarker group BEFREE The aim of this study was to clarify the mechanism underlying ATP7B-mediated copper detoxification by investigating endogenous ATP7B localization in the HepG2 hepatoma cell line and its ability to mediate vesicular sequestration of excess intracellular copper. 16472602 2006
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.340 GeneticVariation group BEFREE Defective cellular localization of mutant ATP7B in Wilson's disease patients and hepatoma cell lines. 12557139 2003
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.340 Biomarker group CTD_human Incidences of spontaneous liver tumors in LEC, WKAH.C-Atp7b and WKAH rats correlated with hepatic copper and iron concentrations. 11509115 2001