Disease: Mild cognitive disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1270972
Disease: Mild cognitive disorder
Mild cognitive disorder 		0.030 AlteredExpression disease BEFREE Our data showed higher TREM2 levels in allele ε4 of apolipoprotein E (ApoE ε4) carriers than non-carriers in MCI and particularly in MCI-AD. 29377401 2018
CUI: C1270972
Disease: Mild cognitive disorder
Mild cognitive disorder 		0.030 AlteredExpression disease BEFREE Additionally, no study has examined the association of peripheral TREM2 levels with neuroimaging measures in AD and MCI. 28453482 2017
CUI: C1270972
Disease: Mild cognitive disorder
Mild cognitive disorder 		0.030 GeneticVariation disease BEFREE Independent voxel-based morphometry analysis of the Spanish set as well as conjunction and joint analyses revealed substantial gray matter loss in orbitofrontal cortex and anterior cingulate cortex with relative preservation of parietal lobes in AD and/or mild cognitive impairment TREM2 p.R47H carriers, suggesting that TREM2 p.R47H variant is associated with certain clinical and neuroimaging AD features in addition to the increased TREM2 p.R47H atrophy in temporal lobes as described previously. 25027412 2014