GPR85, G protein-coupled receptor 85, 54329

N. diseases: 5; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement 		0.100 GeneticVariation phenotype GWASCAT The impact of low-frequency and rare variants on lipid levels. 25961943 2015
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.020 Biomarker disease BEFREE The findings in females and during the emotional memory paradigm are consistent with modulation by SREB2 of brain circuitries implicated in mood regulation and may be relevant to neuropsychiatric conditions other than schizophrenia. 22968816 2013
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.020 Biomarker disease BEFREE Because of phenotypic overlap between SREB2 Tg mice and schizophrenia, we sought a possible link between the two. 18413613 2008
CUI: C0004936
Disease: Mental disorders
Mental disorders 		0.010 Biomarker group BEFREE Our data implicate SREB2 as a potential risk factor for psychiatric disorders and its pathway as a target for psychiatric therapy. 18413613 2008
CUI: C0233514
Disease: Abnormal behavior
Abnormal behavior 		0.010 Biomarker phenotype BEFREE Our data implicate SREB2 as a potential risk factor for psychiatric disorders and its pathway as a target for psychiatric therapy. 18413613 2008
CUI: C0233794
Disease: Memory impairment
Memory impairment 		0.010 AlteredExpression phenotype BEFREE Mild overexpression of SREB2 caused significant brain weight reduction and ventricular enlargement in transgenic (Tg) mice as well as behavioral abnormalities mirroring psychiatric disorders, e.g., decreased social interaction, abnormal sensorimotor gating, and impaired memory. 18413613 2008