POLR2G, RNA polymerase II subunit G, 5436

N. diseases: 13; N. variants: 1
Disease: Primary sclerosing cholangitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0566602
Disease: Primary sclerosing cholangitis
Primary sclerosing cholangitis 		0.010 GeneticVariation disease BEFREE The SNP, rs35730843, mapping to the POLR2G gene promoter (P = 1.2 × 10<sup>-5</sup>, OR = 0.39) demonstrated the highest effect size, and was protective for PBC, whereas for PSC respective SNPs were: rs13191240 in the intron of ADGRB3 gene (P = 0.0095, OR = 0.2) and rs3822659 (P = 0.0051, OR = 0.236) along with rs9686714 (P = 0.00077, OR = 0.2), both located in the WWC1 gene. 28056976 2017