However, no significant differences in genotype frequencies of other tested polymorphisms (PON1-192, PON2-311, GSTM1/T1) and male infertility were observed.
The results indicated that the PON1 Arg192Glu (rs662) and SOD2 Val16Ala (rs4880) variant genotypes were associated with a significantly higher risk of male infertility.
The results indicated that the PON1Arg192Glu (rs662) and SOD2 rs4880" genes_norm="6648;6649">Val16Ala (rs4880) variant genotypes were associated with a significantly higher risk of male infertility.
We speculate that the low activity of PON1 can be a risk factor for male infertility probably due to a decrease in antioxidant activity of PON1 and increase in lipid peroxidation.