POU6F1, POU class 6 homeobox 1, 5463

N. diseases: 10; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0019618
Disease: Histiocytosis
Histiocytosis 		0.010 Biomarker disease BEFREE We reviewed 73 biopsies from 42 patients showing involvement by histiocytosis from a variety of organ systems, including bone (16), retroperitoneum (11), skin (19), orbit (6), brain (5), lung (6), cardiac structures (2), epidural soft tissue (3), oral cavity (2), subcutaneous soft tissue (2), and testis (2). 29192649 2018
CUI: C0026961
Disease: Mydriasis
Mydriasis 		0.010 GeneticVariation phenotype BEFREE In the univariate analysis, factors associated with an unfavorable outcome were preoperative coagulopathy, midline shift of the brain ≥ 5 mm, basal cistern effacement, moderate to severe TBI, hypotension, fixed and dilated pupils, surgical site infection, hematocrit < 30% on admission, coup contusion, and subdural hematoma. 30544306 2018
CUI: C0029182
Disease: orbit (eye disorders)
orbit (eye disorders) 		0.010 Biomarker group BEFREE We reviewed 73 biopsies from 42 patients showing involvement by histiocytosis from a variety of organ systems, including bone (16), retroperitoneum (11), skin (19), orbit (6), brain (5), lung (6), cardiac structures (2), epidural soft tissue (3), oral cavity (2), subcutaneous soft tissue (2), and testis (2). 29192649 2018
CUI: C0398597
Disease: Histiocytic syndrome
Histiocytic syndrome 		0.010 Biomarker disease BEFREE We reviewed 73 biopsies from 42 patients showing involvement by histiocytosis from a variety of organ systems, including bone (16), retroperitoneum (11), skin (19), orbit (6), brain (5), lung (6), cardiac structures (2), epidural soft tissue (3), oral cavity (2), subcutaneous soft tissue (2), and testis (2). 29192649 2018
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar 		0.010 Biomarker disease BEFREE Brain 5-HT1A binding potential (BP(F) = B(max)/K(D), where B(max) = total available receptors, and 1/K(D) = ligand affinity) was measured in 32 currently depressed, medication-free BD subjects and 47 controls. 19278673 2009
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.010 AlteredExpression group BEFREE The results of the present study suggest that the transcription factor POU6F1 could be a new molecular target for treatment of this cancer. 19874398 2009
CUI: C0206681
Disease: Adenocarcinoma, Clear Cell
Adenocarcinoma, Clear Cell 		0.010 AlteredExpression disease BEFREE POU6F1 is the transcription factor that might be involved in cell proliferation of clear cell adenocarcinoma of the ovary. 19874398 2009
CUI: C0948216
Disease: Ovarian adenocarcinoma
Ovarian adenocarcinoma 		0.010 AlteredExpression disease BEFREE POU6F1 is the transcription factor that might be involved in cell proliferation of clear cell adenocarcinoma of the ovary. 19874398 2009
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.010 AlteredExpression group BEFREE The results of the present study suggest that the transcription factor POU6F1 could be a new molecular target for treatment of this cancer. 19874398 2009