Disease: Adult Liver Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0220630
Disease: Adult Liver Carcinoma
Adult Liver Carcinoma 		0.050 AlteredExpression disease BEFREE Considering the possibility that MYC may amplify the expression of PPARA target genes to potentiate cell proliferation and liver cancer, gene expression was analyzed from livers of wild-type and liver-specific Myc knockout (Myc<sup>ΔHep</sup> ) mice treated with the PPARA agonist pirinixic acid. 30697791 2019
CUI: C0220630
Disease: Adult Liver Carcinoma
Adult Liver Carcinoma 		0.050 Biomarker disease BEFREE In addition, a number of concurrent molecular and cellular events have been classified as modulating factors, because they potentially alter the ability of PPARα activators to increase rodent liver cancer while not being key events themselves. 29197930 2018
CUI: C0220630
Disease: Adult Liver Carcinoma
Adult Liver Carcinoma 		0.050 Biomarker disease BEFREE Activation of mouse, but not human, PPARα induces hepatocellular proliferation, hepatomegaly, and liver cancer. 25991671 2015
CUI: C0220630
Disease: Adult Liver Carcinoma
Adult Liver Carcinoma 		0.050 Biomarker disease BEFREE There have been no reports, however, demonstrating that PPARα is involved in the development of human liver cancer. 22168458 2011
CUI: C0220630
Disease: Adult Liver Carcinoma
Adult Liver Carcinoma 		0.050 Biomarker disease BEFREE Peroxisome proliferator-activated receptor alpha: role in rodent liver cancer and species differences. 9924174 1999