PPIA, peptidylprolyl isomerase A, 5478

N. diseases: 180; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2062441
Disease: Influenza A
Influenza A
0.020 Biomarker disease BEFREE Cyclophilin A (CypA) is a peptidyl-prolyl cis/trans isomerase that interacts with the matrix protein (M1) of influenza A virus (IAV) and restricts virus replication by regulating the ubiquitin-proteasome-mediated degradation of M1. 30328013 2018
CUI: C2062441
Disease: Influenza A
Influenza A
0.020 Biomarker disease BEFREE However, recent studies demonstrated that CyPA also possesses a repressive effect on the replication of some viruses like Influenza A virus and rotavirus. 22814107 2012