RNF43, ring finger protein 43, 54894

N. diseases: 88; N. variants: 9
Disease: Pancreatic Ductal Adenocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1335302
Disease: Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma 		0.030 GeneticVariation disease BEFREE We conducted genome-wide CRISPR-Cas9 screens in RNF43-mutant pancreatic ductal adenocarcinoma (PDAC) cells, which rely on Wnt signaling for proliferation. 27869803 2017
CUI: C1335302
Disease: Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma 		0.030 AlteredExpression disease BEFREE In the present study, the expression of the tumor suppressor RNF43 was examined in human patient samples of pancreatic ductal adenocarcinoma (PDAC). 26240024 2016
CUI: C1335302
Disease: Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma 		0.030 GeneticVariation disease BEFREE Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma. 23847203 2013