Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001948
Disease: Alcohol consumption
Alcohol consumption 		0.100 GeneticVariation phenotype GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
CUI: C0871470
Disease: Systolic Pressure
Systolic Pressure 		0.100 GeneticVariation phenotype GWASCAT Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. 29912962 2018
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.010 Biomarker disease BEFREE Among all differentially expressed genes of GBM, CYGB (<i>r</i> = 0.5551; <i>P</i> < 0.0001), ISLR2 (<i>r</i> = 0.5126; <i>P</i> < 0.0001), RPP25 (<i>r</i> = 0.5333; <i>P</i> < 0.0001) and SOX2 (<i>r</i> = -0.4838; <i>P</i> < 0.0001) were strongly correlated with PLK2. 31763067 2019
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.010 AlteredExpression disease BEFREE Significant alterations in the autism cohort included decreased expression (-45%) of RPP25 (15q24.1), which is located within the autism susceptibility locus, 15q22-26. 20632321 2010
CUI: C0006111
Disease: Brain Diseases
Brain Diseases 		0.010 Biomarker group BEFREE Taken together, these findings suggest a potential role for the RPP25 gene transcript in the neurobiology of developmental brain disorders. 20632321 2010
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder 		0.010 AlteredExpression group BEFREE RPP25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder. 20632321 2010
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders 		0.010 AlteredExpression disease BEFREE RPP25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder. 20632321 2010
CUI: C0220748
Disease: Cartilage-hair hypoplasia
Cartilage-hair hypoplasia 		0.010 GeneticVariation disease BEFREE Also other CHH-associated P3 mutations reduced the efficiency by which the RNase MRP RNA is bound by Rpp25-Rpp20. 18164267 2008