|
Autistic Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
<b>Conclusions:</b> The analysis of available literature seems to indicate that there is an association between social cognition dysfunctions in the course of autism and selected alleles of polymorphisms within the OXT receptor AVP 1A receptor genes.
|
31214061 |
2019 |
|
Autistic Disorder
|
0.400 |
Biomarker
|
disease |
BEFREE |
AVP, especially in its inhaled form, seems to be safe and beneficial in improving social functioning including in children with autism.
|
31331023 |
2019 |
|
Autistic Disorder
|
0.400 |
Biomarker
|
disease |
BEFREE |
We analyzed the best of published literature dealing with the relationships between neurohypophyseal hormones and neuropsychiatric conditions like autism (AD), major depressive disorder (MDD), bipolar disorder (BD) and schozophrenia, identifying keywords and MeSH terms in Pubmed and then searching them.
|
29468985 |
2018 |
|
Autistic Disorder
|
0.400 |
Biomarker
|
disease |
BEFREE |
These findings indicate that AVP may be a promising CSF marker of autism's social deficits.Ann Neurol 2018;84:611-615.
|
30152888 |
2018 |
|
Autistic Disorder
|
0.400 |
Biomarker
|
disease |
BEFREE |
These results strongly suggest that changes in structure and FC in brain regions containing AVP may be involved in the etiology of autism.
|
28258508 |
2017 |
|
Autistic Disorder
|
0.400 |
Biomarker
|
disease |
BEFREE |
We hypothesize that alleles of polymorphisms in the promoter region of <i>AVPR1A</i> may differentially interact with certain transcriptional factors, which in turn affect quantitative traits, such as sociality, in children with autism.
|
28808521 |
2017 |
|
Autistic Disorder
|
0.400 |
Biomarker
|
disease |
BEFREE |
This will include the (1) DRD4 gene associated with attentiondeficit/ hyperactivity disorder, located in a locus that underwent a positive selection; the (2) GABRB2 gene, a gene associated with schizophrenia and recently reported as the target of a positive selection; (3) MARK1, a candidate gene for autism that was reported as displaying a signature of adaptative evolution in the human lineage, and (4) the ADH and ALDH2 genes which are associated with alcoholism, and for which evidence of positive selection was identified in the human lineage since the divergence between humans and chimpanzees.
|
20166940 |
2010 |
|
Autistic Disorder
|
0.400 |
Biomarker
|
disease |
BEFREE |
Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between.
|
18655900 |
2008 |
|
Autistic Disorder
|
0.400 |
Biomarker
|
disease |
BEFREE |
Association between the arginine vasopressin 1a receptor (AVPR1a) gene and autism in a family-based study: mediation by socialization skills.
|
16520824 |
2006 |
|
Autistic Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The single nucleotide polymorphism of AVP receptors in the context of complex genetic traits is currently being investigated, and preliminary findings have been reported in arterial hypertension and autism.
|
14972085 |
2004 |
|
Autistic Disorder
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Given the emerging biological, animal model, and now genetic data, AVPR1a and genes in the AVP system remain strong candidates for involvement in autism susceptibility and deserve continued scrutiny.
|
15098001 |
2004 |
|
Autistic Disorder
|
0.400 |
Biomarker
|
disease |
CTD_human |
Low-dose naltrexone effects on plasma chemistries and clinical symptoms in autism: a double-blind, placebo-controlled study.
|
8570775 |
1995 |