Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE These data demonstrated that FBXW7-mediated STAT2 stability regulation plays an essential role in melanoma cell proliferation and cancer growth. 31843895 2020
CUI: C0025202
Disease: melanoma
melanoma 		0.040 AlteredExpression disease BEFREE Here, we report that loss of FBXW7 enhances a mitochondrial gene transcriptional program that is dependent on MITF in human melanoma and confers poor patient outcomes. 29665239 2018
CUI: C0025202
Disease: melanoma
melanoma 		0.040 GeneticVariation disease BEFREE We found FBXW7 to be mutated in eight (8.1%) melanoma patients in our cohort (n = 103). 24838835 2014
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE Taken together, our findings indicate that Fbw7 has an important role in melanoma progression, and it inhibits melanoma cell migration through the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and may serve as a prognostic marker. 23381582 2013