This article was retracted because of inappropriate use of confidential material and text available to one of the authors through the review of “TRPV6 As A Target For Cancer Therapy”, John M Stewart, J.
Calcium uptake in epithelial tissues is mediated by tetrameric calcium-selective transient receptor potential (TRP) channels TRPV6 that are implicated in a variety of human diseases, including numerous forms of cancer.
Here we show that ∼95% of cervical tumor samples examined overexpress Cat-1, suggesting that the up-regulation of Cat-1 expression is a frequent occurrence in this type of cancer.