LYAR, Ly1 antibody reactive, 55646

N. diseases: 9; N. variants: 0
Disease: Virus Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.010 Biomarker group BEFREE In summary, our study reveals the mechanism of LYAR in modulating IFN-β-mediated innate immune responses by targeting phosphorylated IRF3, which not only helps us to better understand the mechanisms of LYAR-regulated virus replication but also uncovers a novel role of LYAR in host innate immunity.<b>IMPORTANCE</b> Type I interferon (IFN-I) plays a critical role in the antiviral innate immune responses that protect the host against virus infection. 31413131 2019