Disease: Presenile dementia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.320 Biomarker disease BEFREE SLC30A6 has been implicated in Alzheimer disease, so these fusion gene data could explain a report of spastic paraplegia and dementia cosegregating in a family with deletion of the final exon of SPAST. 25065914 2014
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.320 AlteredExpression disease BEFREE Furthermore, we propose that genomic deletions encompassing the final exon of SPAST may affect expression of SLC30A6, the most proximal downstream locus and a gene that has been implicated in the pathogenesis of Alzheimer disease, potentially explaining recent reports of dementia in selected SPG4 patients. 21659953 2011
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.320 Biomarker disease CTD_human Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain. 16580781 2006