PRKCB, protein kinase C beta, 5579

N. diseases: 317; N. variants: 18
Disease: Meniere Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025281
Disease: Meniere Disease
Meniere Disease 		0.310 Biomarker disease BEFREE Taken together, our findings identify PRKCB gene as a novel candidate gene for familial MD and its expression gradient in supporting cells of the organ of Corti deserves attention, given the role of supporting cells in K<sup>+ </sup>recycling within the endolymph, and its apical turn location may explain the onset of hearing loss at low frequencies in MD. 27329761 2016
CUI: C0025281
Disease: Meniere Disease
Meniere Disease 		0.310 Biomarker disease GENOMICS_ENGLAND Identification of two novel mutations in FAM136A and DTNA genes in autosomal-dominant familial Meniere's disease. 25305078 2015