Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
Knockdown of SCN3B in LQTS3/BrS iPSC-derived cardiomyocytes successfully unmasked the phenotype of BrS.
|
27677334 |
2016 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
Contribution of Cardiac Sodium Channel β-Subunit Variants to Brugada Syndrome.
|
26179811 |
2015 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
Genomic DNA extracted from the blood samples of 123 medico-legal autopsy-negative SUNDS cases and 104 sex-, age- and ethnic-matched controls from Southern China underwent comprehensive amino acid coding region mutational analysis for the BrS associated genes SCN5A, SCN1B, SCN2B, SCN3B, SCN4B, MOG1, and GPD1-L using PCR and direct sequencing.
|
24529773 |
2014 |
Brugada Syndrome (disorder)
|
0.530 |
GeneticVariation
|
disease |
BEFREE |
The Val110Ile mutation of SCN3B is a relatively common cause of SCN5A-negative BrS in Japan, which has a reduced sodium current because of the loss of cell surface expression of Nav1.5.
|
23257389 |
2013 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
The Val110Ile mutation of SCN3B is a relatively common cause of SCN5A-negative BrS in Japan, which has a reduced sodium current because of the loss of cell surface expression of Nav1.5.
|
23257389 |
2013 |
Brugada Syndrome (disorder)
|
0.530 |
GeneticVariation
|
disease |
BEFREE |
Previously BrS-associated mutations in KNCD3 and SCN3B were also present in ESP data.
|
22284586 |
2012 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation.
|
21051419 |
2011 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
Sudden infant death syndrome-associated mutations in the sodium channel beta subunits.
|
20226894 |
2010 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties.
|
19351516 |
2009 |
Brugada Syndrome (disorder)
|
0.530 |
GeneticVariation
|
disease |
BEFREE |
A missense mutation (L10P) was detected in exon 1 of SCN3B, the beta 3 subunit of the cardiac sodium channel, but not in any other gene known to be associated with Brugada syndrome or in 296 controls.
|
20031595 |
2009 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
MGD |
Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties.
|
19351516 |
2009 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
A missense mutation (L10P) was detected in exon 1 of SCN3B, the beta 3 subunit of the cardiac sodium channel, but not in any other gene known to be associated with Brugada syndrome or in 296 controls.
|
20031595 |
2009 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
Modulation of Na(v)1.5 by beta1-- and beta3-subunit co-expression in mammalian cells.
|
15455233 |
2005 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
Distinct subcellular localization of different sodium channel alpha and beta subunits in single ventricular myocytes from mouse heart.
|
15007009 |
2004 |
Brugada Syndrome (disorder)
|
0.530 |
Biomarker
|
disease |
CLINGEN |
The sodium channel beta-subunit SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart.
|
11744748 |
2001 |