PRKCI, protein kinase C iota, 5584

N. diseases: 78; N. variants: 3
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker disease BEFREE Circular RNA PRKCI promotes glioma cell progression by inhibiting microRNA-545. 31409777 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.040 AlteredExpression disease BEFREE Protein kinase C-iota (PKC-ι) is an oncogene overexpressed in many cancer cells including prostate, breast, ovarian, melanoma, and glioma. 30204596 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker disease BEFREE Since, PKC-ι is an essential downstream mediator of the PI (3)-kinase, we hypothesize that glioma cell survival is mediated via a PI (3)-kinase/PDK1/PKC-ι/Bad pathway. 21419810 2011
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker disease LHGDN Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-iota in human glioma cells. 15695176 2005