PRKCI, protein kinase C iota, 5584

N. diseases: 78; N. variants: 3
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 Biomarker group BEFREE In this article, we report a co-up-regulation and colocalization of MT1-MMP and atypical protein kinase C iota (aPKCι) in hormone receptor-negative breast tumors in association with a higher risk of metastasis. 24753582 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 AlteredExpression group LHGDN The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors. 18538170 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 AlteredExpression group LHGDN Atypical PKC-zeta and PKC-iota mediate opposing effects on MCF-7 Na+/K+ATPase activity. 15887250 2005