PKN2, protein kinase N2, 5586

N. diseases: 29; N. variants: 7
Disease: Hepatitis C ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019196
Disease: Hepatitis C
Hepatitis C 		0.020 GeneticVariation disease BEFREE The kinase C-related kinase 2 (PRK2), which phosphorylates hepatitis C virus (HCV) RNA polymerase, is a proviral factor enhancing HCV replication. 30127498 2018
CUI: C0019196
Disease: Hepatitis C
Hepatitis C 		0.020 Biomarker disease BEFREE Thus, as Ser76 is absolutely conserved across HCV genotypes, our results confirmed the relevance of these sites for both genotypes and suggested that Ser76 becomes phosphorylated by a cellular kinase different from PRK2. 26301630 2015