PRKCZ, protein kinase C zeta, 5590

N. diseases: 88; N. variants: 8
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.340 AlteredExpression disease BEFREE Overall, NP induced human CRC COLO205 cell proliferation and inhibited the apoptotic rate of COLO205 cells by increasing the activity of PKCζ and ERK1/2. 30675313 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.340 Biomarker disease BEFREE PKCζ is a tumor suppressor in CRC with reduced expression in metastasis. 29694894 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.340 Biomarker disease BEFREE Protein kinase C zeta (PKCz) controls mitotic spindle dynamics, chromosome segregation, and multicellular patterns, but its role in CRC phenotype evolution remains unclear. 29520890 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.340 Biomarker disease BEFREE Collectively, PKCζ could be a novel oncogenic protein of human CRC. 29029434 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.340 GeneticVariation disease UNIPROT