PRKCZ, protein kinase C zeta, 5590

N. diseases: 88; N. variants: 8
Disease: Hyperglycemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.220 AlteredExpression disease BEFREE In vivo hyperglycemia/hyperinsulinemia in rats for 48 hours similarly resulted in activation of PKC-ζ and increased phosphorylation of IRS-1 Ser318 and Akt Thr34. 29370351 2018
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.220 Biomarker disease BEFREE Furthermore, either kinase-dead PKCζ expression (KD-PKCζ) or disruption of PKCζ in mouse β-cells blocks compensatory β-cell replication when acute hyperglycemia/hyperinsulinemia is induced. 26868297 2016
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.220 Biomarker disease RGD Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats. 12960081 2003