Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684256
Disease: Bacterial sepsis
Bacterial sepsis
0.010 Biomarker disease BEFREE The pathogenesis of AKI in sepsis is incompletely understood.In this issue of the JCI, Hato et al. investigate the renal translatome during bacterial sepsis and identify the global shutdown of renal protein translation mediated by the eukaryotic translation initiation factor 2-α kinase 2/eukaryotic translation initiation factor 2α (EIF2AK2/eIF2α) axis as a major pathway in mediating septic AKI. 30507607 2019