Disease: Endothelial dysfunction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.010 AlteredExpression phenotype BEFREE ERS inhibition in DOCA-salt induced hypertension was observed to have reduced systolic blood pressure, improved endothelial dysfunction, enhanced plasma nitric oxide (NO) level, reduced protein expressions of phosphorylated-double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (pPERK), 78 kDa glucose-regulated protein (GRP78), Inositol trisphosphate receptor1 (IP<sub>3</sub>R1) and Epidermal growth factor receptor (EGFR), increased expressions of endoplasmic reticulum Ca<sup>2+</sup>-ATPase2 (SERCA2) and B cell lymphoma2 (Bcl2) in vessels. 30458302 2019