PRLR, prolactin receptor, 5618

N. diseases: 110; N. variants: 15
Disease: Primary malignant neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 AlteredExpression group BEFREE The expression of PRLR, phosphorylated Janus-kinase 2 (pJAK2), estrogen receptor-α, progesterone receptor, and PTEN in cancer tissue were evaluated by immunohistochemistry.Ninety-nine patients were identified. 29901521 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 AlteredExpression group BEFREE Ectopic expression of prolactin receptor in mouse cancer cells enhances micrometastasis, while treatment with the COX-2 inhibitor celecoxib abrogates prolactin secretion by fibroblasts and reduces tumor initiation. 30819896 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 AlteredExpression group BEFREE The results revealed that ERα, ERβ, PRLR and Ki67 expression levels were increased during the progression of cancer. 30272319 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 Biomarker group BEFREE Prolactin receptor (PRLR) is overexpressed in breast and prostate cancers and is a new target for cancer therapy. 29684277 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 Biomarker group BEFREE These features endow PRLR-targeted imaging with the potential to transform ovarian cancer detection.<i>Cancer Res; 77(7); 1684-96.©2017 AACR</i>. 28202518 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 AlteredExpression group BEFREE Prolactin and prolactin receptor expression in cervical intraepithelial neoplasia and cancer. 24990775 2015
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 AlteredExpression group BEFREE Quantification of prolactin receptor mRNA in multiple human tissues and cancer cell lines by real time RT-PCR. 11572805 2001