PRNP, prion protein, 5621

N. diseases: 426; N. variants: 47
Disease: Convulsive Seizures ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751494
Disease: Convulsive Seizures
Convulsive Seizures 		0.010 Biomarker phenotype BEFREE Aβ-induced dendritic spine loss and lactate dehydrogenase release required both PrP(C) and Fyn, and human familial Alzheimer's disease transgene-induced convulsive seizures did not occur in mice lacking PrP(C). 22820466 2012