PRNP, prion protein, 5621

N. diseases: 426; N. variants: 47
Disease: Acquired CJD ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2931859
Disease: Acquired CJD
Acquired CJD 		0.030 GeneticVariation disease BEFREE The transmission properties of acquired CJD-MMiK were quite different from those of sporadic CJD with the same PRNP codon 129 genotype. 29329906 2018
CUI: C2931859
Disease: Acquired CJD
Acquired CJD 		0.030 Biomarker disease BEFREE Thus, we propose that the distinctive combination of 129 M/M genotype, kuru plaques, and intermediate type PrP(Sc) , represents a reliable criterion for the identification of acquired CJD cases among presumed sporadic cases. 26669818 2016
CUI: C2931859
Disease: Acquired CJD
Acquired CJD 		0.030 GeneticVariation disease BEFREE PrP(Sc) isoforms derived from wild-type and mutant PrP are distinct both from each other and from those seen in sporadic and acquired CJD. 16597650 2006