PRODH, proline dehydrogenase 1, 5625

N. diseases: 85; N. variants: 17
Disease: Schizoaffective Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036337
Disease: Schizoaffective Disorder
Schizoaffective Disorder 		0.010 GeneticVariation disease BEFREE In a previous report [Jacquet et al., 2005] we have shown that mild to moderate hyperprolinemia resulting from several alterations (either a complete deletion or missense mutations) of the proline dehydrogenase (PRODH) gene located on chromosome 22q11 is a risk factor for schizoaffective disorder but not for DSM3 R schizophrenia or bipolar disorder. 16389584 2006