GKN1, gastrokine 1, 56287
N. diseases: 55; N. variants: 0
Source: ALL
| Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year |
|---|---|---|---|---|---|---|---|
|
|
0.070 | AlteredExpression | disease | BEFREE | Helicobacter pylori inhibits GKN1 expression via the CagA/p-ERK/AUF1 pathway. | 31657090 | 2020 |
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0.070 | Biomarker | disease | BEFREE | Gastrokine 1 inhibits the carcinogenic potentials of Helicobacter pylori CagA. | 25239641 | 2014 |
|
|
0.070 | AlteredExpression | disease | BEFREE | GKN1 is downregulated in Helicobacter pylori-infected gastric epithelial cells and loss of GKN1 expression is closely associated with gastric carcinogenesis, but underlying mechanisms of the tumor-suppressing effects of GKN1 remain largely unknown. | 23846337 | 2013 |
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|
0.070 | AlteredExpression | disease | BEFREE | GKN1 is down-regulated in Helicobacter pylori-infected gastric epithelial cells and loss of GKN1 expression is tightly associated with gastric carcinogenesis. | 24099765 | 2013 |
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0.070 | AlteredExpression | disease | BEFREE | Furthermore, gastrokine 1 gene expression was markedly lower in gastric cancer tissues of Helicobacter pylori (HP)-positive patients than negative ones (P<0.05). | 23317277 | 2012 |
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|
0.070 | AlteredExpression | disease | BEFREE | Expression of gastrokine-1 protein was decreased in Helicobacter pylori-positive chronic gastritis compared with Helicobacter pylori-negative subjects and the healthy controls. | 22798109 | 2012 |
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|
0.070 | AlteredExpression | disease | BEFREE | Molecular expression of Gastrokine 1 in normal mucosa and in Helicobacter pylori-related preneoplastic and neoplastic gastric lesions. | 18927498 | 2008 |