PROX1, prospero homeobox 1, 5629

N. diseases: 114; N. variants: 10
Disease: Lymphatic Metastasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024232
Disease: Lymphatic Metastasis
Lymphatic Metastasis 		0.010 AlteredExpression disease BEFREE Subsequently, exosomal LNMAT2 was internalized by HLECs and epigenetically upregulated prospero homeobox 1 (PROX1) expression by recruitment of hnRNPA2B1 and increasing the H3K4 trimethylation level in the PROX1 promoter, ultimately resulting in lymphangiogenesis and lymphatic metastasis. 31593555 2020