PROX1, prospero homeobox 1, 5629

N. diseases: 114; N. variants: 10
Disease: Papillary thyroid carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.030 AlteredExpression disease BEFREE Altered Prox1 expression has been found in a variety of human cancers, including papillary thyroid carcinoma (PTC). 29371975 2017
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.030 AlteredExpression disease BEFREE Here, we report that the regulator of cell fate specification, PROX1, becomes inactivated in PTC through mRNA downregulation and cytoplasmic mislocalization. 26609053 2016
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		0.030 Biomarker disease BEFREE Conversely, the introduction of a PROX1 transgene into a papillary thyroid cancer and anaplastic thyroid cancer cells induced the expression of SG-related genes. 26760117 2016