PRTN3, proteinase 3, 5657

N. diseases: 215; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0544786
Disease: wegener's granuloma
wegener's granuloma
0.020 Biomarker disease BEFREE Pathways to ANCA production: from differentiation of dendritic cells by proteinase 3 to B lymphocyte maturation in Wegener's granuloma. 18181035 2008
CUI: C0544786
Disease: wegener's granuloma
wegener's granuloma
0.020 Biomarker disease BEFREE Aggregates of B lymphocytes proximal to PR3+ cells as well as plasma cells have been described as substantial components of Wegener's granuloma and could participate in forming tertiary lymphoid structures, which might promote autoantibody formation. 18826496 2008