Retinoblastoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
CEA family syndrome. Abnormal carcinoembryonic antigen (CEA) levels in asymptomatic retinoblastoma family members.
|
1260660 |
1976 |
Malignant tumor of colon
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
CEA mRNA did not appear to correlate with metastasis because its expression in the primary colon cancers with metastases (Dukes' stage D tumor) was not always increased.
|
1290028 |
1992 |
Neoplasm Metastasis
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
CEA mRNA did not appear to correlate with metastasis because its expression in the primary colon cancers with metastases (Dukes' stage D tumor) was not always increased.
|
1290028 |
1992 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
CEA mRNA did not appear to correlate with metastasis because its expression in the primary colon cancers with metastases (Dukes' stage D tumor) was not always increased.
|
1290028 |
1992 |
Secondary Neoplasm
|
0.100 |
AlteredExpression
|
group |
BEFREE |
CEA mRNA did not appear to correlate with metastasis because its expression in the primary colon cancers with metastases (Dukes' stage D tumor) was not always increased.
|
1290028 |
1992 |
Colorectal Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Application of genetically-engineered anti-CEA antibodies for potential immunotherapy of colorectal cancer.
|
1431347 |
1992 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Hitherto anti-CEA monoclonal antibodies (MAbs), normally of mouse origin, have been used primarily for clinical diagnosis of colorectal cancer, either as a tumor marker in serum to monitor tumor recurrence, or latterly as a means to localize in vivo CEA-bearing tumors, and metastases in patients.
|
1431347 |
1992 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Hitherto anti-CEA monoclonal antibodies (MAbs), normally of mouse origin, have been used primarily for clinical diagnosis of colorectal cancer, either as a tumor marker in serum to monitor tumor recurrence, or latterly as a means to localize in vivo CEA-bearing tumors, and metastases in patients.
|
1431347 |
1992 |
Secondary Neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
Hitherto anti-CEA monoclonal antibodies (MAbs), normally of mouse origin, have been used primarily for clinical diagnosis of colorectal cancer, either as a tumor marker in serum to monitor tumor recurrence, or latterly as a means to localize in vivo CEA-bearing tumors, and metastases in patients.
|
1431347 |
1992 |
Malignant neoplasm of colon and/or rectum
|
0.100 |
Biomarker
|
disease |
BEFREE |
Application of genetically-engineered anti-CEA antibodies for potential immunotherapy of colorectal cancer.
|
1431347 |
1992 |
Recurrent tumor
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
Hitherto anti-CEA monoclonal antibodies (MAbs), normally of mouse origin, have been used primarily for clinical diagnosis of colorectal cancer, either as a tumor marker in serum to monitor tumor recurrence, or latterly as a means to localize in vivo CEA-bearing tumors, and metastases in patients.
|
1431347 |
1992 |
Mesothelioma
|
0.030 |
Biomarker
|
disease |
BEFREE |
The PAS and CEA reactions are negative but the vimentin and cytokeratin are positive in mesothelioma.
|
1464814 |
1993 |
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Localization of CEA messenger RNA by in situ hybridization in normal colonic mucosa and colorectal adenocarcinomas.
|
1484322 |
1992 |
Colorectal Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
CEA mRNA was detectable by northern blot hybridization in 97% of the CRCs examined.
|
1962152 |
1991 |
Carcinoma of lung
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
CEA mRNA was detected together with NCA mRNA in nine cultured cell lines, with the exception of the lung carcinoma A549 cell line, and in 19 colon tissue specimens, including carcinomas, adjacent noninvaded tissues and adenomas.
|
2067130 |
1991 |
Adenoma
|
0.020 |
AlteredExpression
|
group |
BEFREE |
CEA mRNA was detected together with NCA mRNA in nine cultured cell lines, with the exception of the lung carcinoma A549 cell line, and in 19 colon tissue specimens, including carcinomas, adjacent noninvaded tissues and adenomas.
|
2067130 |
1991 |
Carcinoma breast stage IV
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
All mucin markers which were investigated showed improved sensitivity for metastatic breast cancer compared with the established marker CEA.
|
2068512 |
1991 |
Small cell carcinoma of lung
|
0.050 |
Biomarker
|
disease |
BEFREE |
CEA was detectable in 5/6 SCLC cell lines but absent in non-SCLC, and its level seemed to correlate with those of DDC, NSE, and CK.
|
2438285 |
1987 |
Acute Promyelocytic Leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
A pregnancy-specific beta 1-glycoprotein, a CEA gene family member, expressed in a human promyelocytic leukemia cell line, HL-60: structures of protein, mRNA and gene.
|
2789512 |
1989 |
Promyelocytic leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
A pregnancy-specific beta 1-glycoprotein, a CEA gene family member, expressed in a human promyelocytic leukemia cell line, HL-60: structures of protein, mRNA and gene.
|
2789512 |
1989 |
Colonic Neoplasms
|
0.040 |
AlteredExpression
|
group |
BEFREE |
CEA mRNA is most strongly expressed in primary colon tumors and, to a lesser extent, in normal colonic tissue.
|
3033671 |
1987 |
Ulcerative Colitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Many polyps and dysplastic lesions in ulcerative colitis have phenotypic changes (blood group antigen, cytokeratins, CEA, TAG-72.3 antigen expression) and genetic changes (c-K-ras mutation, enhanced c-myc expression and pp60c-src activity) which are characteristic of invasive cancers.
|
3052255 |
1988 |
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
No circulating CEA was found in patients bearing widespread metastatic disease of MA-CEA positive lesions.
|
3235849 |
1989 |
Carcinoma
|
0.090 |
AlteredExpression
|
group |
BEFREE |
Similarly to the 180 kd CEA molecules synthesized by carcinomas, the expression of the melanoma associated CEA like components (MA-CEA) is upregulated by IFN-alpha.
|
3235849 |
1989 |
Adenoma of large intestine
|
0.010 |
Biomarker
|
disease |
BEFREE |
Aneuploidy and expression of gastric-associated mucus antigens M1 and CEA in colorectal adenomas.
|
3544799 |
1987 |