PYY, peptide YY, 5697

N. diseases: 88; N. variants: 14
Disease: Obesity, Morbid ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028756
Disease: Obesity, Morbid
Obesity, Morbid 		0.020 GeneticVariation disease BEFREE Genetic variants of genes for peptide YY (PYY), neuropeptide Y2 receptor (NPY2R) and pancreatic polypeptide (PPY) were investigated for association with severe obesity. 17235527 2007
CUI: C0028756
Disease: Obesity, Morbid
Obesity, Morbid 		0.020 GeneticVariation disease BEFREE However, if the analysis was restricted to men (n = 167, 100 obese and 67 lean), the PYY variants and two SNPs in Y2R that were in complete linkage disequilibrium were significantly associated with severe obesity (P = 0.001 and P = 0.002, respectively). 15855352 2005