Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.060 Biomarker disease BEFREE Previous studies have proposed that overexpression of CD36, GGPPS, PTP-1B, GRK2, and adipose triglyceride lipase may contribute to the development of metabolic syndrome, and Pueraria could eliminate the metabolic adverse effects. 30946280 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.060 AlteredExpression disease BEFREE This study suggests that adipose HuR may be a critical regulator of ATGL expression and lipolysis and thereby controls obesity and metabolic syndrome. 31147543 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.060 Biomarker disease BEFREE Pro-inflammatory cytokines related to insulin resistance and MetS in children are tumor necrosis factor-alpha (TNF-α), interleukin (IL)-6, IL-1β, interferon gamma, pigment epithelium-derived factor, chemerin, vaspin, and fetuin A. Anti-inflammatory cytokines associated with insulin resistance and MetS in children are leptin, adiponectin, omentin, fibroblast growth factor (FGF)-21, osteocalcin, and irisin. 30338401 2018
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.060 AlteredExpression disease BEFREE Pigment epithelium-derived factor (PEDF) is an antiinflammatory protein that circulates at high levels in the metabolic syndrome. 24456163 2014
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.060 AlteredExpression disease BEFREE Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome. 22551950 2012
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.060 Biomarker disease BEFREE These results complement previous findings of functional studies in mammals and elucidate a potential role of ATGL in pathways involved in components of the metabolic syndrome. 16644682 2006