BAD, BCL2 associated agonist of cell death, 572

N. diseases: 125; N. variants: 2
Disease: ovarian neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.020 PosttranslationalModification disease BEFREE BAD phosphorylation determines ovarian cancer chemosensitivity and patient survival. 21849418 2011
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.020 PosttranslationalModification disease LHGDN Our findings suggest that paclitaxel induces the phosphorylation of BAD Ser-112 via the ERK cascade, and the phosphorylation of both BAD Ser-136 and Raf-1 Ser-259 via the PI-3K-Akt cascade, and that inhibition of either of these cascades sensitizes ovarian cancer cells to paclitaxel. 12087097 2002