PTGER3, prostaglandin E receptor 3, 5733

N. diseases: 82; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma
0.230 Therapeutic disease RGD Adenosine A(1) and prostaglandin E receptor 3 receptors mediate global airway contraction after local epithelial injury. 23221044 2013
CUI: C0004096
Disease: Asthma
Asthma
0.230 GeneticVariation disease BEFREE Our findings provide further evidence that polymorphisms in PTGER3 might play a significant role in aspirin hypersensitivity among Korean asthmatics. 20587336 2010
CUI: C0004096
Disease: Asthma
Asthma
0.230 GeneticVariation disease LHGDN Association between genetic variations in prostaglandin E2 receptor subtype EP3 gene (Ptger3) and asthma in the Korean population. 17877755 2007
CUI: C0004096
Disease: Asthma
Asthma
0.230 GeneticVariation disease BEFREE Through association analyses studies of the 32 single nucleotide polymorphisms, the following single nucleotide polymorphisms were found to have significant associations with the aspirin-intolerant asthma phenotype: -616C>G (P=0.038) and -166G>A (P=0.023) in PTGER2; -1709T>A (P=0.043) in PTGER3; -1254A>G (P=0.018) in PTGER4; 1915T>C (P=0.015) in PTGIR; and -4684C>T (P=0.027), and 795T>C (P=0.032) in TBXA2R. 17496729 2007