|
Arteriosclerosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
A candidate gene approach identified upregulated miR-431-5p encoded in the conserved 12qF1 (14q32 in humans) microRNA cluster, whose expression correlated with blood pressure, and which has been shown to be upregulated in human atherosclerosis, as a potential key regulator in Ang II-induced vascular injury.
|
30929512 |
2019 |
|
Atherosclerosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
A candidate gene approach identified upregulated miR-431-5p encoded in the conserved 12qF1 (14q32 in humans) microRNA cluster, whose expression correlated with blood pressure, and which has been shown to be upregulated in human atherosclerosis, as a potential key regulator in Ang II-induced vascular injury.
|
30929512 |
2019 |
|
Malignant tumor of colon
|
0.010 |
Biomarker
|
disease |
BEFREE |
Collectively, ATG3 upregulation, caused by downregulated miR-435-5p, promotes proliferation and invasion via an autophagy-dependent manner in colon cancer suggesting that miR-431-5p/ATG3/autophagy may be a potential therapeutic target in colon cancer.
|
31849517 |
2019 |
|
Hirschsprung Disease
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Upregulation of miR-431-5p and downregulation of LRSAM1 were found in ENCCs of HSCR.
|
31037734 |
2019 |
|
Hypertensive disease
|
0.010 |
Biomarker
|
group |
BEFREE |
In vivo miR-431-5p knockdown delayed Ang II-induced blood pressure elevation and reduced vascular injury in mice, which demonstrated its potential as a target for treatment of hypertension and vascular injury.
|
30929512 |
2019 |
|
Respiratory Distress Syndrome, Newborn
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Our previous study demonstrated that miR‑431 was differentially expressed between infants with RDS and infants without RDS using microarray analysis.
|
31059017 |
2019 |
|
Rhabdomyosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
<i>NOTCH2</i>, <i>FGFR1/2</i> were significantly down-modulated in AYA-RMS. miR-223 was associated with up-regulation of epithelial mesenchymal translation (EMT) and inflammatory pathways, whereas miR-431 was correlated to myogenic differentiation and muscle metabolism.
|
31533233 |
2019 |
|
Agenesis of corpus callosum
|
0.010 |
Biomarker
|
disease |
BEFREE |
microRNA-431 (miR-431) was underexpressed in patients with ACC with progressive disease undergoing adjuvant therapy.
|
30918109 |
2019 |
|
Adrenocortical carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
microRNA-431 as a Chemosensitizer and Potentiator of Drug Activity in Adrenocortical Carcinoma.
|
30918109 |
2019 |
|
Childhood Rhabdomyosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
<i>NOTCH2</i>, <i>FGFR1/2</i> were significantly down-modulated in AYA-RMS. miR-223 was associated with up-regulation of epithelial mesenchymal translation (EMT) and inflammatory pathways, whereas miR-431 was correlated to myogenic differentiation and muscle metabolism.
|
31533233 |
2019 |
|
Adult Rhabdomyosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
<i>NOTCH2</i>, <i>FGFR1/2</i> were significantly down-modulated in AYA-RMS. miR-223 was associated with up-regulation of epithelial mesenchymal translation (EMT) and inflammatory pathways, whereas miR-431 was correlated to myogenic differentiation and muscle metabolism.
|
31533233 |
2019 |
|
Aplasia Cutis Congenita
|
0.010 |
Biomarker
|
disease |
BEFREE |
microRNA-431 (miR-431) was underexpressed in patients with ACC with progressive disease undergoing adjuvant therapy.
|
30918109 |
2019 |
|
Squamous cell carcinoma of tongue
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our results demonstrated that circ_0001742 plays a tumor-promoting effect in TSCC cells by serving as a competing endogenous RNA (ceRNA) to regulate miR-431-5p/ATF3 axis, which might provide a potential therapeutic target for TSCC.
|
31841185 |
2019 |
|
Necrotizing Enterocolitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Z., Chan, K. Y. Y., Leung, K. T., Lam, H. S., Tam, Y. H., Lee, K. H., Li, K., Ng, P. C. Dysregulation of miR-431 and target gene FOXA1 in intestinal tissues of infants with necrotizing enterocolitis.
|
30624964 |
2019 |
|
Progressive Neoplastic Disease
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
microRNA-431 (miR-431) was underexpressed in patients with ACC with progressive disease undergoing adjuvant therapy.
|
30918109 |
2019 |
|
Colon Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Collectively, ATG3 upregulation, caused by downregulated miR-435-5p, promotes proliferation and invasion via an autophagy-dependent manner in colon cancer suggesting that miR-431-5p/ATG3/autophagy may be a potential therapeutic target in colon cancer.
|
31849517 |
2019 |
|
Progressive cGVHD
|
0.010 |
Biomarker
|
disease |
BEFREE |
microRNA-431 (miR-431) was underexpressed in patients with ACC with progressive disease undergoing adjuvant therapy.
|
30918109 |
2019 |
|
Necrotizing enterocolitis in fetus OR newborn
|
0.010 |
Biomarker
|
disease |
BEFREE |
The objective of this study was to identify the target gene of miR-431 and to investigate the role of the miR-431-FOXA1 axis in the pathophysiology of NEC.
|
30624964 |
2019 |
|
Alzheimer's Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our findings demonstrate that miR-431 protects synapses and neurites from Aβ-toxicity in an AD cell culture model and may be a promising therapeutic target.
|
29643768 |
2018 |
|
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Furthermore, hsa-miR-323b-3p may be related to DLBCL by participating in pathways in cancer. hsa-miR-431-5p may also play a role in DLBCL by regulating FYN.
|
29128636 |
2018 |
|
Cerebral Infarction
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Rho expression and cerebral infarction were visualized by immunohischemistry and TTC staining, respectively. qRT-PCR and western blotting were used to measure mRNA and protein expression of miR-431 and Rho/Rho-kinase signaling pathway-related genes.
|
29227541 |
2018 |
|
Colorectal Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The low expression of miR-431 in colorectal cancer patients is involved in the development of colorectal cancer by promoting the migration of colorectal cancer cells.
|
29863249 |
2018 |
|
Leukemia, Myelocytic, Acute
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
MicroRNAs (miR)-133 and -431 that target Evi1 were investigated, and it was observed that there was a low expression of miR-431 in AML.
|
30013666 |
2018 |
|
Diffuse Large B-Cell Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Furthermore, hsa-miR-323b-3p may be related to DLBCL by participating in pathways in cancer. hsa-miR-431-5p may also play a role in DLBCL by regulating FYN.
|
29128636 |
2018 |
|
Intervertebral Disc Degeneration
|
0.010 |
Biomarker
|
disease |
BEFREE |
CircSEMA4B targets miR-431 modulating IL-1β-induced degradative changes in nucleus pulposus cells in intervertebral disc degeneration via Wnt pathway.
|
30251693 |
2018 |