|
Papillary thyroid carcinoma
|
0.310 |
Biomarker
|
disease |
BEFREE |
Our results indicated that miR-431 could serve as a predictor for PTC patients with positive lymph node metastasis and a potential target of PTC treatment.
|
29945344 |
2018 |
|
Papillary thyroid carcinoma
|
0.310 |
Biomarker
|
disease |
CTD_human |
Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer.
|
28030816 |
2017 |
|
Neoplasms, Experimental
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer.
|
28030816 |
2017 |
|
Nonmedullary Thyroid Carcinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer.
|
28030816 |
2017 |
|
Familial Nonmedullary Thyroid Cancer
|
0.300 |
Biomarker
|
disease |
CTD_human |
Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer.
|
28030816 |
2017 |
|
Tumor Cell Invasion
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
MiR-431 is a prognostic marker and suppresses cell growth, migration and invasion by targeting NOTCH2 in melanoma.
|
31115015 |
2019 |
|
Tumor Cell Invasion
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
Furthermore, luciferase report system, plate clone formation and Transwell invasion assays demonstrated that miR-431-5p could prohibit cell proliferation and invasion via directly targeting ATG3 in colon cancer.
|
31849517 |
2019 |
|
Tumor Cell Invasion
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
In conclusion, we found that miR-431 inhibited the migration and invasion of trophoblastic cells by targeting ZEB1, which might give rise to the onset of PE.
|
30315928 |
2019 |
|
Tumor Cell Invasion
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
The transfection of miR-431 also suppressed the migration and invasion of AML cells.
|
30013666 |
2018 |
|
Tumor Cell Invasion
|
0.070 |
AlteredExpression
|
phenotype |
BEFREE |
Downregulation of MiR-431 expression associated with lymph node metastasis and promotes cell invasion in papillary thyroid carcinoma.
|
29945344 |
2018 |
|
Tumor Cell Invasion
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
Mechanistically, it was discovered that miR-431-5p repressed invasion by targeting <i>UROC28</i>.
|
30323624 |
2018 |
|
Tumor Cell Invasion
|
0.070 |
AlteredExpression
|
phenotype |
BEFREE |
MiR-431 down-expression was correlated with multiple malignant characteristics, including lymph node metastasis (r = -0.455, P < 0.001), clinical TNM stage (r = -0.223, P = 0.030), MTDH (r = -0.292, P = 0.006), vaso-invasion (r = -0.204, P = 0.047), MVD (r = -0.281, P = 0.006) and HCV (r = 0.215, P = 0.037).
|
25775917 |
2015 |
|
Neoplasm Metastasis
|
0.030 |
AlteredExpression
|
phenotype |
BEFREE |
Down-regulation of miR-431 accelerated cell growth and metastasis of H1650 cells.
|
30720177 |
2019 |
|
Neoplasm Metastasis
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
Besides, the restoration of NOTCH2 significantly reversed the inhibitory effects of miR-431 on melanoma cells growth and metastasis.
|
31115015 |
2019 |
|
Neoplasm Metastasis
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
Our results indicated that miR-431 could serve as a predictor for PTC patients with positive lymph node metastasis and a potential target of PTC treatment.
|
29945344 |
2018 |
|
Liver carcinoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
These data suggest that the rs112395617 polymorphism may contribute to HCC susceptibility, in full or at least partially through an effect on <i>JAK1</i> transcriptional activity by disrupting its binding with miR-431-5p.
|
29731916 |
2018 |
|
Liver carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
The current study has demonstrated that the miR-431-5p/<i>UROC28</i> axis acts possible influence on the EMT in HCC.
|
30323624 |
2018 |
|
Liver carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
These results suggest hsa_circ_0005075 promotes HCC via miR-431 regulation.
|
29710484 |
2018 |
|
Glioblastoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Mechanism of microRNA-431-5p-<i>EPB41L1</i> interaction in glioblastoma multiforme cells.
|
31749885 |
2019 |
|
melanoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
MiR-431 expression in melanoma cell lines and carcinomas tissues were detected using RT-PCR.
|
31115015 |
2019 |
|
Malignant neoplasm of lung
|
0.020 |
Biomarker
|
disease |
BEFREE |
Molecular mechanism exploration uncovered that FBXL19-AS1 acted as a molecular sponge of miR-431-5p and that RAF1 was a downstream target of miR-431-5p in lung cancer.
|
30610161 |
2019 |
|
Malignant neoplasm of lung
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
MiR-431 expression was significantly lower in 122 lung cancer tissue samples or cell lines compared to the adjacent normal tissues or lung bronchial epithelial cell line, respectively.
|
30720177 |
2019 |
|
Carcinoma of lung
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
MiR-431 expression was significantly lower in 122 lung cancer tissue samples or cell lines compared to the adjacent normal tissues or lung bronchial epithelial cell line, respectively.
|
30720177 |
2019 |
|
Carcinoma of lung
|
0.020 |
Biomarker
|
disease |
BEFREE |
Molecular mechanism exploration uncovered that FBXL19-AS1 acted as a molecular sponge of miR-431-5p and that RAF1 was a downstream target of miR-431-5p in lung cancer.
|
30610161 |
2019 |
|
Primary malignant neoplasm of lung
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
MiR-431 expression was significantly lower in 122 lung cancer tissue samples or cell lines compared to the adjacent normal tissues or lung bronchial epithelial cell line, respectively.
|
30720177 |
2019 |