|
Parathyroid Adenoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The main outcome measures were serum total calcium, ionized calcium, intact parathyroid hormone (PTH), albumin, alkaline phosphatase, phosphate, 25-hydroxy vitamin D, 1,25-dihydroxy vitamin D, 24-h urinary calcium levels, and parathyroid adenoma weight.
|
30289305 |
2019 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>Abbreviations: BNE</b> = bilateral neck exploration; <b>CT</b> = computed tomography; <b>IOPTH</b> = intra-operative parathyroid hormone; <b>MGD</b> = multi-gland disease; <b>MIBI</b> = sestamibi; <b>MIP</b> = minimally invasive parathyroidectomy; <b>MRI</b> = magnetic resonance imaging; <b>PHPT</b> = primary hyperparathyroidism; <b>PTA</b> = parathyroid adenoma; <b>PTH</b> = parathyroid hormone; <b>SGA</b> = single-gland adenoma; <b>SPECT</b> = single photon emission computed tomography; <b>4D</b> = four-dimensional.
|
30720353 |
2019 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to investigate the accuracy of the parathyroid hormone needle aspiration washout method in detecting the localization of parathyroid adenoma.
|
30834899 |
2019 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Median serum Ca was significantly higher in atypical parathyroid adenoma patients than parathyroid hyperplasia patients (P = 0.019) and median PTH was significantly higher in APA compared to PA patients (P<0.001).
|
31751311 |
2019 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Laboratory testing demonstrated elevated calcium and parathyroid hormone supporting diagnosis of parathyroid adenoma.
|
30702621 |
2019 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Differences in Tc-MIBI DPS, serum parathyroid hormone (PTH), serum calcium and phosphorus, as well as the weight and longest diameter of lesion between PA and PH were also compared.
|
30239472 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Diagnostic accuracy of parathyroid hormone levels in washout samples of suspicious parathyroid adenomas: A single-centre retrospective cohort study.
|
30004132 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In case two, the high level of parathyroid hormone (PTH) and the scintigraphy scan showing parathyroid gland adenoma confirmed primary hyperparathyroidism-induced hypercalcemia.
|
29951343 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Patients with cystic parathyroid adenomas had higher serum intact parathyroid hormone and calcium levels, larger maximum tumor diameter, and lower serum inorganic phosphorus level than did those with solid adenomas.
|
30123260 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
It is caused by autonomic oversecretion of parathyroid hormone (PTH) owing to parathyroid adenoma, hyperplasia, or tumor.
|
30383698 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
[<sup>18</sup>F]Fluorocholine Uptake of Parathyroid Adenoma Is Correlated with Parathyroid Hormone Level.
|
29508264 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
There was a positive correlation between the weight of the adenoma and serum PTH and calcium (Ca) levels (P<0.001), between serum PTH and Ca levels (P<0.001), early PT-T and serum Ca levels (P=0.027), late PT-T and weight of the adenoma (P=0.04), and PT SPECT and serum Ca levels (P=0.046) and a reverse correlation between PT SPECT and serum phosphorus (P) levels (P=0.04).
|
29360693 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Among the analysed parameters including serum calcium and PTH and the size and weight of parathyroid adenomas, size was significantly different between patients with negative <sup>99m</sup>Tc-MIBI/tetrofosmin SPECT/CT and those with positive <sup>99m</sup>Tc-MIBI/tetrofosmin SPECT/CT (mean size 13.4 ± 7.6 mm vs. 16.9 ± 7.4 mm, respectively; p = 0.042).
|
29516131 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
In case of hypercalcemia, serum intact PTH and parathyroid imaging should be monitored to evaluate the presence of parathyroid adenoma with care because PHPT could present with inappropriate normal PTH.
|
29995768 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Primary hyperparathyroidism is commonly caused by excess production of parathyroid hormone from sporadic parathyroid adenomas.
|
29982334 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We report here an interference that has been observed with 2<sup>nd</sup> generation PTH assays (PTH2), but not with 3<sup>rd</sup> generation PTH ones (PTH3), during PTH monitoring occurring in a surgical intervention for the resection of a parathyroid adenoma.
|
29233774 |
2018 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
THE RESULTS OF PARATHYROID HORMONE ASSAY IN PARATHYROID ASPIRATES IN PRE-OPERATIVE LOCALIZATION OF PARATHYROID ADENOMAS FOR FOCUSED PARATHYROIDECTOMY IN PATIENTS WITH NEGATIVE OR SUSPICIOUS TECHNETIUM-99M-SESTAMIBI SCANS.
|
28683236 |
2017 |
|
Parathyroid Adenoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
To validate the accuracy of intraoperative measurements of parathyroid hormone levels in parathyroid adenomas.
|
29235733 |
2017 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
A 73-year-old man displaying primary hyperparathyroidism with severe hypercalcemia (Ca: 4.1 mmol/l, PTH > 600 pmol/l) was referred for preoperative localization of a parathyroid adenoma.
|
28033216 |
2017 |
|
Parathyroid Adenoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In patients with primary hyperparathyroidism, preoperative calcium and PTH levels may be predictive of parathyroid adenoma dimensions.
|
27696726 |
2017 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The effect of chronic elevation of PTH was evaluated in 20 patients affected by PHP at diagnosis and after surgical removal of parathyroid adenoma.
|
26068297 |
2015 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Forty-one parathyroid adenomas from patients with symptomatic PHPT and ten normal parathyroid glands either from patients with PHPT (n=3) or from euthyroid patients without PHPT during thyroid surgery (n=7) were analyzed for vitamin D receptor (VDR), calcium-sensing receptor (CASR), cyclin D1 (CD1), and parathyroid hormone (PTH) expressions.
|
23660642 |
2013 |
|
Parathyroid Adenoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The inhibitory effect of Ca(2+) calmodulin on PTH secretion may be due to the absence of synaptotagmin 1 protein in parathyroid adenomas, as demonstrated by western blot analysis.
|
20974637 |
2011 |
|
Parathyroid Adenoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Southern blot analyses of the parathyroid adenoma revealed rearrangement in the PTH gene locus.
|
20641034 |
2010 |
|
Parathyroid Adenoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The aim of the study was to determine: 1) Klotho expression in parathyroid adenomas from patients with primary hyperparathyroidism (pHPT) compared to normal tissue; and 2) its relation to the serum calcium and PTH levels.
|
18682507 |
2008 |