|
Papillary thyroid carcinoma
|
0.310 |
Biomarker
|
disease |
BEFREE |
To the best of our knowledge, these findings demonstrate for the first time that miR-409-3p functions as a tumor suppressor in PTC and could serve as an efficient agent for therapy of PTC.
|
30250593 |
2018 |
|
Papillary thyroid carcinoma
|
0.310 |
Biomarker
|
disease |
CTD_human |
Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer.
|
28030816 |
2017 |
|
Carcinoid Tumor
|
0.310 |
AlteredExpression
|
phenotype |
BEFREE |
MiR-409-3p, miR-409-5p and miR-431-5p were also significantly downregulated in carcinoids metastatic to the lymph nodes.
|
25791280 |
2015 |
|
Carcinoid Tumor
|
0.310 |
Biomarker
|
phenotype |
CTD_human |
Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA.
|
25105010 |
2014 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.300 |
Biomarker
|
disease |
CTD_human |
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
|
28545106 |
2017 |
|
Nonmedullary Thyroid Carcinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer.
|
28030816 |
2017 |
|
Familial Nonmedullary Thyroid Cancer
|
0.300 |
Biomarker
|
disease |
CTD_human |
Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer.
|
28030816 |
2017 |
|
Lung Neoplasms
|
0.300 |
Biomarker
|
group |
CTD_human |
Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA.
|
25105010 |
2014 |
|
Carcinoid, Goblet Cell
|
0.300 |
Biomarker
|
disease |
CTD_human |
Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA.
|
25105010 |
2014 |
|
Malignant neoplasm of lung
|
0.300 |
Biomarker
|
disease |
CTD_human |
Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA.
|
25105010 |
2014 |
|
Argentaffinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA.
|
25105010 |
2014 |
|
Hepatoma, Morris
|
0.300 |
Biomarker
|
disease |
CTD_human |
Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages.
|
21035526 |
2011 |
|
Hepatoma, Novikoff
|
0.300 |
Biomarker
|
disease |
CTD_human |
Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages.
|
21035526 |
2011 |
|
Liver Neoplasms, Experimental
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages.
|
21035526 |
2011 |
|
Precancerous Conditions
|
0.300 |
Biomarker
|
group |
CTD_human |
Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages.
|
21035526 |
2011 |
|
Experimental Hepatoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages.
|
21035526 |
2011 |
|
Condition, Preneoplastic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages.
|
21035526 |
2011 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Compared with paracancerous and normal liver tissues, the level of microRNA-409 was remarkably reduced in hepatocarcinoma tissues and was negatively correlated with tumor stage, tumor size and overall survival time of patients with liver cancer.
|
30657556 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
These findings indicated that miR‑409 targeted the Smad2 transcript and suppressed endometrial cancer cell growth, suggesting that miR‑409 has a tumor suppressive role in the pathogenesis of human endometrial cancer.
|
30431090 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Taken together, our observations highlight the potential role of miR-409-3p as a tumor suppressor in OS partially through down-regulation of ZEB1 and suggest that miR-409-3p has potential applications in OS treatment.
|
30846940 |
2019 |
|
Tumor Cell Invasion
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Resumption of miR-409-3p expression attenuated OS cell proliferation and invasion.
|
30846940 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Additionally, a tumor xenograft model was constructed to examine the effects of miR-409-3p on the tumor growth and lymphatic metastasis in nude mice.
|
29928443 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
To the best of our knowledge, these findings demonstrate for the first time that miR-409-3p functions as a tumor suppressor in PTC and could serve as an efficient agent for therapy of PTC.
|
30250593 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
MiR-409-5p was aberrantly upregulated in both breast cancer tumors and cell lines.
|
28459205 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Taken together, our findings collectively indicate that miR-409-3p may be a tumor suppressor in osteosarcoma and may serve as a promising therapeutic target for osteosarcoma.
|
28286730 |
2017 |