MIR146B, microRNA 146b, 574447

N. diseases: 187; N. variants: 1
Disease: Thyroid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.070 Biomarker disease BEFREE Systemic injection of an anti-miR-146b in mice with orthotopic thyroid tumors suppressed tumor growth and recovered DICER1 levels. 30967628 2019
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.070 Biomarker disease BEFREE Interestingly, miR-146b inhibition in human thyroid tumor xenografts, using a synthetic and clinically amenable molecule, blocked tumor growth when delivered intratumorally. 29353884 2018
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.070 Biomarker disease BEFREE MiR146b-5P plays important roles in the progression of multiple cancers including thyroid cancer, pancreatic cancer, cervical cancer. 30206978 2018
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.070 AlteredExpression disease BEFREE Moreover, expression of miR-146b-5p and miR-146b-3p was further higher in thyroid metastatic nodes than thyroid cancer. 30244634 2018
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.070 AlteredExpression disease BEFREE However, the utility of in situ hybridization (ISH) to determine the cellular localization, diagnostic, and prognostic significance of miR-146b-5p and miR-21 expression in thyroid tumors has not been extensively analyzed. 25771986 2015
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.070 Biomarker disease BEFREE MiR-146b-5p promotes metastasis and induces epithelial-mesenchymal transition in thyroid cancer by targeting ZNRF3. 25547151 2015
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.070 Biomarker disease BEFREE MicroRNA miR-146b-5p regulates signal transduction of TGF-β by repressing SMAD4 in thyroid cancer. 21874046 2012