PTK2, protein tyrosine kinase 2, 5747

N. diseases: 205; N. variants: 21
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.100 Biomarker group BEFREE SMARCE1-mediated PTK2 activation likely plays a key role in promoting metastasis of basal-like and luminal B subtype of breast tumors. 27495308 2016
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.100 AlteredExpression group BEFREE Transcripts of FAK expressed in 102 human breast tumor tissues and 52 corresponding normal tissues were analyzed by RT-PCR and DNA sequencing, as well as agarose gel electrophoresis. 24885534 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.100 AlteredExpression group BEFREE FAK mRNA expression was also found to correlate with TP53 mutation status in a series of breast tumors. 21071137 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.100 AlteredExpression group LHGDN The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells. 19029090 2009
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.100 Biomarker group LHGDN Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness. 18832579 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.100 PosttranslationalModification group LHGDN Phosphorylation of FAK, PI-3K, and impaired actin organization in CK-positive micrometastatic breast cancer cells. 17515959 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.100 Biomarker group LHGDN Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer. 16412380 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.100 AlteredExpression group LHGDN Specific induction of pp125 focal adhesion kinase in human breast cancer. 16136050 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.100 Biomarker group LHGDN Inhibition of focal adhesion kinase by antisense oligonucleotides enhances the sensitivity of breast cancer cells to camptothecins. 12847914 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.100 Biomarker group LHGDN Functional involvement of src and focal adhesion kinase in a CD99 splice variant-induced motility of human breast cancer cells. 12216109 2002