|
Malignant neoplasm of breast
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Here, polyamidoamine grafted halloysite nanotubes (PAMAM- g-HNTs) were synthesized for loading of siRNA in order to intracellular delivery of siRNA and treat of breast cancer via gene therapy.
|
29947505 |
2018 |
|
Crohn Disease
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
|
18587394 |
2008 |
|
Breast Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Here, polyamidoamine grafted halloysite nanotubes (PAMAM- g-HNTs) were synthesized for loading of siRNA in order to intracellular delivery of siRNA and treat of breast cancer via gene therapy.
|
29947505 |
2018 |
|
Liver carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
miR-125b-5p inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma via targeting <i>TXNRD1</i>.
|
31384178 |
2019 |
|
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
Malignant neoplasm of lung
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Here, we report the dysregulation of mutant MET originally found in a lung cancer patient with Val370 to Asp370 (V370D) replacement located in the extracellular SEMA domain.
|
31342590 |
2019 |
|
Malignant neoplasm of lung
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
From 1 July 2015 to 20 February 2016, 100 patients with COPD and lung cancer, 100 patients with COPD without lung cancer and 100 healthy smokers were enrolled at the Shanghai Ruijin Hospital (Shanghai, China) for the genotyping of eight single-nucleotide polymorphisms (SNPs; ex3P36A_C>G, ex3S41Y_C>A, ex4V113A_T>C, ex4P174Y_G>T, ex6P275A_C>G, ex6R293×_C>T, ex10G369S_G>A and ex11H441R_A>G) via gene sequencing.
|
29731913 |
2018 |
|
Carcinoma of lung
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
From 1 July 2015 to 20 February 2016, 100 patients with COPD and lung cancer, 100 patients with COPD without lung cancer and 100 healthy smokers were enrolled at the Shanghai Ruijin Hospital (Shanghai, China) for the genotyping of eight single-nucleotide polymorphisms (SNPs; ex3P36A_C>G, ex3S41Y_C>A, ex4V113A_T>C, ex4P174Y_G>T, ex6P275A_C>G, ex6R293×_C>T, ex10G369S_G>A and ex11H441R_A>G) via gene sequencing.
|
29731913 |
2018 |
|
Carcinoma of lung
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Here, we report the dysregulation of mutant MET originally found in a lung cancer patient with Val370 to Asp370 (V370D) replacement located in the extracellular SEMA domain.
|
31342590 |
2019 |
|
Primary malignant neoplasm of lung
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
Here, we report the dysregulation of mutant MET originally found in a lung cancer patient with Val370 to Asp370 (V370D) replacement located in the extracellular SEMA domain.
|
31342590 |
2019 |
|
Primary malignant neoplasm of lung
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
From 1 July 2015 to 20 February 2016, 100 patients with COPD and lung cancer, 100 patients with COPD without lung cancer and 100 healthy smokers were enrolled at the Shanghai Ruijin Hospital (Shanghai, China) for the genotyping of eight single-nucleotide polymorphisms (SNPs; ex3P36A_C>G, ex3S41Y_C>A, ex4V113A_T>C, ex4P174Y_G>T, ex6P275A_C>G, ex6R293×_C>T, ex10G369S_G>A and ex11H441R_A>G) via gene sequencing.
|
29731913 |
2018 |
|
Ehlers-Danlos Syndrome
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Phenotypic variability of the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VIA): clinical, molecular and biochemical delineation.
|
21699693 |
2011 |
|
Ehlers-Danlos Syndrome
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Kyphoscoliotic type of Ehlers-Danlos Syndrome (EDS VIA) in six Egyptian patients presenting with a homogeneous clinical phenotype.
|
25277362 |
2015 |
|
Ehlers-Danlos Syndrome
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Mutation analysis of the PLOD1 gene: an efficient multistep approach to the molecular diagnosis of the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VIA).
|
15979919 |
2006 |
|
Malignant neoplasm of stomach
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Conclusively, our results manifested that miR-599 possessed the function of tumor suppressor gene in regulating EMT and metastasizing GC via targeting EIF5A2.
|
29091897 |
2018 |
|
Stomach Carcinoma
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Conclusively, our results manifested that miR-599 possessed the function of tumor suppressor gene in regulating EMT and metastasizing GC via targeting EIF5A2.
|
29091897 |
2018 |
|
Mental disorders
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Mice with mutations in Sema6A or the interacting genes may thus represent a highly informative model for how neurodevelopmental defects can lead to anatomical dysconnectivity, resulting, either directly or through reactive mechanisms, in dysfunction at the level of neuronal networks with associated behavioural phenotypes of relevance to psychiatric disorders.
|
22132072 |
2011 |
|
Mental disorders
|
0.020 |
GeneticVariation
|
group |
BEFREE |
The findings presented in this study are part of the multicenter SEMA study (Subjective Experience and Medication Adherence in Adolescents with Psychiatric Disorders).
|
30148662 |
2018 |
|
Chronic Obstructive Airway Disease
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
From 1 July 2015 to 20 February 2016, 100 patients with COPD and lung cancer, 100 patients with COPD without lung cancer and 100 healthy smokers were enrolled at the Shanghai Ruijin Hospital (Shanghai, China) for the genotyping of eight single-nucleotide polymorphisms (SNPs; ex3P36A_C>G, ex3S41Y_C>A, ex4V113A_T>C, ex4P174Y_G>T, ex6P275A_C>G, ex6R293×_C>T, ex10G369S_G>A and ex11H441R_A>G) via gene sequencing.
|
29731913 |
2018 |
|
Mucocutaneous Lymph Node Syndrome
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Functional proof-of-principle studies demonstrated that increased levels of select SEMA pathway genes are associated with decreased self-renewal and growth in vitro and in vivo and that RHO signaling, known to mediate the effects of SEMA genes, is contributing to the OTX2 KD phenotype.
|
29377567 |
2018 |
|
nervous system disorder
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Mutations in the PLA2G6 gene which encodes Ca(2+)-independent phospholipase A2 (VIA iPLA2) were detected in 85% of cases of the inherited degenerative nervous system disorder INAD (infantile neuroaxonal dystrophy, OMIM #256600).
|
27395788 |
2016 |
|
Schizophrenia
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
<b>Discussion:</b> Findings from the VIA 7 study revealed large variations across domains between children born to parents with schizophrenia, bipolar and controls, respectively.
|
30631284 |
2018 |
|
Schizophrenia
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder: the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study.
|
31494772 |
2019 |
|
Abnormal behavior
|
0.020 |
GeneticVariation
|
phenotype |
BEFREE |
Mice with mutations in Sema6A or the interacting genes may thus represent a highly informative model for how neurodevelopmental defects can lead to anatomical dysconnectivity, resulting, either directly or through reactive mechanisms, in dysfunction at the level of neuronal networks with associated behavioural phenotypes of relevance to psychiatric disorders.
|
22132072 |
2011 |
|
Abnormal behavior
|
0.020 |
GeneticVariation
|
phenotype |
BEFREE |
The findings presented in this study are part of the multicenter SEMA study (Subjective Experience and Medication Adherence in Adolescents with Psychiatric Disorders).
|
30148662 |
2018 |