KIAA1549, KIAA1549, 57670

N. diseases: 64; N. variants: 0
Disease: Astrocytoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.330 GeneticVariation disease BEFREE Analysis of KIAA1549-BRAF fusion gene expression and IDH1/IDH2 mutations in low grade pediatric astrocytomas. 24532263 2014
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.330 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.330 AlteredExpression disease BEFREE BRAF gene rearrangements that were indicated in three tumors prompted the discovery of KIAA1549-BRAF fusion transcripts expressed in 10 of 10 grade 1 astrocytomas and in none of the grade 2 to 4 tumors. 20068183 2010
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.330 Biomarker disease BEFREE As the KIAA1549-BRAF fusion gene is detected at a much lower frequency in diffuse low-grade astrocytomas and survival was much longer than expected in the patients with a 'non-pilocytic' astrocytoma carrying the fusion gene, identification of this fusion gene can be of diagnostic and prognostic value. 20976706 2010