Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.030 Biomarker disease BEFREE Our findings are the first to demonstrate that PTP1B inhibitors could be used in prevention and reversal of atherosclerosis development and reduction in CVD risk. 28899902 2017
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.030 AlteredExpression disease BEFREE Here we demonstrate that inhibiting the activity of PTP1B specifically in myeloid lineage cells protects against atherosclerotic plaque formation, under atherogenic conditions, in an ApoE<sup>-/-</sup> mouse model of atherosclerosis. 28752048 2017
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.030 GeneticVariation disease BEFREE Genetic variation in PTPN1, a diabetes susceptibility gene, was investigated for a role in diabetic atherosclerosis. 16505227 2006