METTL14, methyltransferase like 14, 57721

N. diseases: 27; N. variants: 0
Disease: Tumor Progression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.020 Biomarker phenotype BEFREE Moreover, inhibition of FTO suppresses tumor progression and prolongs lifespan of GSC-grafted mice substantially. m<sup>6</sup>A sequencing reveals that knockdown of METTL3 or METTL14 induced changes in mRNA m<sup>6</sup>A enrichment and altered mRNA expression of genes (e.g., ADAM19) with critical biological functions in GSCs. 28297667 2017
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.020 Biomarker phenotype BEFREE These studies reveal an important role of METTL14 in tumor metastasis and provide a fresh view on m<sup>6</sup> A modification in tumor progression.(Hepatology 2017;65:529-543). 27774652 2017