TRIB3, tribbles pseudokinase 3, 57761

N. diseases: 104; N. variants: 5
Disease: Carotid Atherosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		0.020 GeneticVariation disease BEFREE After adjustment for age, sex and smoking status, rs4675095-T (IRS1) and rs4897549-A (ENPP1) were significantly associated with carotid atherosclerosis severity, whilst rs7265169-A (TRIB3) was associated with ECG abnormalities. 26868433 2016
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		0.020 GeneticVariation disease BEFREE The TRIB3 R84 allele especially predisposes to carotid atherosclerosis in part through the effects of abdominal obesity, hypertriglyceridemia, and insulin resistance. 19389818 2009