Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma
0.030 PosttranslationalModification disease BEFREE Constitutive activation of phosphatase SHP2 was found to negatively regulate IL-6 induced STAT3 phosphorylation in fibroblasts from severe asthmatics. 29242170 2018
CUI: C0004096
Disease: Asthma
Asthma
0.030 Biomarker disease BEFREE Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivo. 28481957 2017
CUI: C0004096
Disease: Asthma
Asthma
0.030 Biomarker disease BEFREE As such, SHP2 represents a potentially novel therapeutic target for the treatment of asthmatics. 23057634 2012