|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Although the NS1 protein is known to play a role in immune modulation, no differences were detected in the limited innate immune response to LPAI virus infection.
|
31683727 |
2019 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
In conclusion, the new FRET-based serological approaches based on NS1 protein are applicable to diagnosing zika virus infections in travelers and differentiating them from other flavivirus infections.
|
31335898 |
2019 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The NS1 protein of influenza virus is a virulence element and the critical factor for regulation of the host immune response during virus infection.
|
31530680 |
2019 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
In this chapter, we mainly focus on recent research on the crystal structures of the ZIKV E and NS1 proteins, and their relations with virus infection and immune responses.
|
29845526 |
2018 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Here, we demonstrate that UAP56 also co-localizes with the influenza A viral NS1 protein, which counteracts host cell innate immune responses stimulated by virus infection.
|
30258431 |
2018 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Here, we developed a reliable reverse genetics system based on the JEV SA14-14-2 strain to further explore the mechanism for the synthesis of NS1' protein and to investigate the function of NS1' protein during virus infection.
|
26384477 |
2015 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
During virus infection NS1 protein has several functions both in the nucleus and in the cytoplasm and its intracellular localization is regulated by one or two nuclear localization signals (NLS) and a nuclear export signal (NES).
|
25023993 |
2014 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The role of LGP2 in virus infection is controversial, and the only LGP2 experiments previously carried out with mammalian influenza A viruses employed an attenuated, mouse-adapted H1N1 A/PR/8/34 (PR8) virus that does not encode the NS1 protein.
|
22837208 |
2012 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
In summary, we established a system to identify cellular factors that interact with NS1 protein during virus infection and furthermore demonstrated that RHA interacts with NS1 and enhances viral replication and transcription.
|
22171255 |
2012 |
|
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
L69,77A NS1 virus infection was not able to activate the PI3K/Akt anti-apoptotic pathway, suggesting that the mutant NS1 protein may not be localized such that it has access to p85β in vivo during infection, which was supported by the altered subcellular localization pattern of the mutant NS1 compared with WT NS1 after transfection or virus infection.
|
21508188 |
2011 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The non-structural (NS1) protein of influenza A viruses is a non-essential virulence factor that has multiple accessory functions during viral infection.
|
18796704 |
2008 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Taken together, our results suggest that the cellular response to influenza A virus infection in human lung cells is significantly influenced by the sequence of the NS1 gene, demonstrating the importance of the NS1 protein in regulating the host cell response triggered by virus infection.
|
12149435 |
2002 |
|
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The prevalence of NS1 Ab response in patients with dengue viral infection and the potential of using recombinant NS1 protein as a diagnostic antigen for dengue viral infection were investigated.
|
11596093 |
2001 |